Herpes is a collective name for diseases, caused by the Herpes simplex virus (HSV). This is one of the most common viruses in humans. There are two types of the HSV. Type 1 is usually responsible for herpes infections on the face and lips (cold sores). Type 2 is usually the cause of herpes infections around the genitals.


When the body is infected with HSV, we speak of a primary (first occurring) infection. The virus enters the body through mucosa or through the skin. It usually takes three to nine days before the symptoms develop. The virus replicates in the infected skin or infected mucosa and spreads to the lymph nodes in the vicinity of the infection site. These lymph nodes may temporarily become bigger and painful.
Characteristic for a herpes infection is that the virus remains lifelong in the body in a dormant form. At an early stage of the primary infection, the virus penetrates the local nerve endings and travels through the nerve to the corresponding ganglion. Due to various circumstances, including fever, sunlight, menstruation or stress, the virus can become active again and move from the ganglion to the initially infected area of the skin or mucosa. Here, an inflammation can reoccur.
Most people are infected with HSV type 1 at a young age. Primary herpes infections in children are usually less severe than in adults. The severity increases with age. The virus has only a short life span outside the human body. Infection mostly occurs via direct contact with a carrier of the virus.


Both virus types can in principle affect any area of the skin and adjacent mucosa.
The signs and symptoms are:


The diagnosis of a herpes infection of skin and mucosa is usually made on the basis of the existing symptoms. By means of laboratory tests, such as microscopic examination, viral culture and DNA techniques, the diagnosis can be confirmed.


Normally, herpes infections don’t require treatment. After all, the symptoms disappear naturally. When treatment of a herpes infection is necessary, an antiviral agent may be prescribed. This drug inhibits multiplication of the virus. There are no drugs available that kill the virus. The infection can thus regularly come back again after the treatment. For herpes to the lips, an antiviral cream can be used. When there is often recurrent herpes, people with many symptoms can be given a long-term treatment with antiviral tablets.


Anyone who has once been infected with the herpes virus, carries the virus with him for life. In most people, this causes no problems. For some, the virus is occasionally active, making the symptoms come back. In a very small group, this happens so often and so intense, that they are really bothered. Eventually, however, even in those people the attacks decrease in severity and number.